Module 8: Quantitative Genetics
Genetic variation is the diversity in gene frequencies between the individual or the differences between population. Different sources of genetic variation are mutation, random mating between organisms, crossing over, and random fertilization. Various factors act to maintain the genetic variation in population such as mutation, selective neutrality, balancing selection, frequency dependent selection, and changing patterns of selection over time or space. Mutation is one of the factors which contribute to rare genetic variation in a population. Selective neutrality arises when there is only a small difference in fitness between the alternate allele of a gene. When the alleles are governed by genetic drift rather than natural selection they are selectively neutral. Balancing selection arises when the heterozygotes have higher fitness than the two homozygous genotypes. These allow both the alleles to be maintained in a population. Frequency dependent selection happen when the individuals ...